ABCC3 CLIA Kit for Human(Homo sapiens) | EIAab.comABCC3 CLIA Kit for Human(Homo sapiens)

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ABCC3 (Gene name),

Canalicular multispecific organic anion transporter 2 (Protein name ), MRP3_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ABCC3(CMOAT2;MLP2;MRP3);

Protein name:

Canalicular multispecific organic anion transporter 2;

Alternative:

Multi-specific organic anion transporter D(MOAT-D);ATP-binding cassette sub-family C member 3;Multidrug resistance-associated protein 3;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes.

Subcellular Location:

Membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

1527

Sequence:

50:

100:

150:

200:

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300:

350:

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450:

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650:

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1150:

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1250:

1300:

1350:

1400:

1450:

1500:

1527:

VAEFDSPANL | IAARGIFYGM | ARDAGLA

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

O15438

STRING:

9606.ENSP00000285238

Pfam:

PF00664

KEGG:

hsa:8714

UniGene:

Hs.463421

String:

O15438

MIM:

604323

Uniprot:

O15438

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ELISA Kit for Human Canalicular multispecific organic anion transporter 2

Cat.:

E10401m

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96T

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ELISA Kit for Human Canalicular multispecific organic anion transporter 2

Cat.:

E10401h

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96T

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ELISA Kit for Human Canalicular multispecific organic anion transporter 2

Cat.:

E10401r

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CLIA Kit for Human Canalicular multispecific organic anion transporter 2

Cat.:

U10401m

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96T

CLIA Kit for Human Canalicular multispecific organic anion transporter 2

Cat.:

U10401r

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96T

CLIA Kit for Human Canalicular multispecific organic anion transporter 2

Cat.:

U10401h

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96T

Polyclonal Antibody for Human Canalicular multispecific organic anion transporter 2

Cat.:

P10401Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Canalicular multispecific organic anion transporter 2

Cat.:

P10401Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Canalicular multispecific organic anion transporter 2

Cat.:

P10401Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Canalicular multispecific organic anion transporter 2

Protein for Human Canalicular multispecific organic anion transporter 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Isolation of a novel human canalicular multispecific organic anion transporter, cMOAT2/MRP3, and its expression in cisplatin-resistant cancer cells with decreased ATP-dependent drug transport."
Uchiumi T. , Hinoshita E. , Haga S. , Nakamura T. , Tanaka T. , Toh S. , Furukawa M. , Kawabe T. , Wada M. , Kagotani K. , Okumura K. , Kohno K. , Akiyama S. , Kuwano M.
Biochem. Biophys. Res. Commun.252:103-110(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Liver.
2.

"cDNA cloning and inducible expression of human multidrug resistance associated protein 3 (MRP3)."
Kiuchi Y. , Suzuki H. , Hirohashi T. , Tyson C.A. , Sugiyama Y.
FEBS Lett.433:149-152(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.

"Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins."
Belinsky M.G. , Bain L.J. , Balsara B.B. , Testa J.R. , Kruh G.D.
J. Natl. Cancer Inst.90:1735-1741(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
4.

"Human MRP3 transporter: identification of the 5'-flanking region, genomic organization and alternative splice variants."
Fromm M.F. , Leake B. , Roden D.M. , Wilkinson G.R. , Kim R.B.
Biochim. Biophys. Acta1415:369-374(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3)
tissue: Liver.
5.

"Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane."
Koenig J. , Rost D. , Cui Y. , Keppler D.
Hepatology29:1156-1163(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Liver.
6.

"Complete coding sequence of human MRP3, a homolog of the human multidrug resistance-associated protein MRP1."
Kool M. , de Haas M. , Ponne N.J. , Baas F. , Borst P.
Submitted (1997-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Liver.
7.

"Identification of a novel splice variant of MRP3 involved in resistance to DNA damaging agents."
Auclair D. , Alonso E. , Chen L.B.
Submitted (1999-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4)
tissue: Colon carcinoma.
8.

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Zody M.C. , Garber M. , Adams D.J. , Sharpe T. , Harrow J. , Lupski J.R. , Nicholson C. , Searle S.M. , Wilming L. , Young S.K. , Abouelleil A. , Allen N.R. , Bi W. , Bloom T. , Borowsky M.L. , Bugalter B.E. , Butler J. , Chang J.L. , more...
Nature440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
10.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 5)
tissue: Blood.
11.

"Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines."
Kool M. , de Haas M. , Scheffer G.L. , Scheper R.J. , van Eijk M.J. , Juijn J.A. , Baas F. , Borst P.
Cancer Res.57:3537-3547(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1043-1527 (ISOFORM 1)
tissue: Liver.
12.

"An unappreciated role for RNA surveillance."
Hillman R.T. , Green R.E. , Brenner S.E.
Genome Biol.5:R8.1-R8.16(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SPLICE ISOFORM(S) THAT ARE POTENTIAL NMD TARGET(S)
13.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.

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